Cynomolgus LGR5 / GPR49 protein, His Tag, Unconjugated, Human

Product Overview

• Article Name: Cynomolgus LGR5 / GPR49 protein, His Tag, Unconjugated, Human
• Biozol Catalog Number: ABS-LG5-C52H7-100UG
• Supplier Catalog Number: LG5-C52H7-100ug
• Alternative Catalog Number: ABS-LG5-C52H7-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Unconjugated

Product Description

LGR5 (also known as GPR49) is a seventransmembrane protein of the class A Rhodopsinlike family of GPCRs. LGR5 and LGR4 bind the Rspondins with high affinity and mediate the potentiation of Wnt/betacatenin signaling by enhancing Wntinduced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. - Proteine/Peptide

Product Properties

• Molecular Weight: 61.7 kDa
• Tag: C-10*His
• NCBI: 7
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: LGR5

Images

Immobilized Cynomolgus LGR5, His Tag (Cat. No. LG5-C52H7) at 5 µg/mL (100 µL/well) can bind Human R-Spondin 1 (21-146), Fc Tag (Cat. No. RS1-H5269) with a linear range of 0.2-5 ng/mL (QC tested).

Immobilized Human R-Spondin 1 (21-146), Fc Tag (Cat. No. RS1-H5269) at 5 µg/mL (100 µL/well) can bind Cynomolgus LGR5, His Tag (Cat. No. LG5-C52H7) with a linear range of 0.1-10 ng/mL (Routinely tested).

Cynomolgus LGR5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.