Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag(TM)
Biozol Catalog Number:
ABS-LG5-H82E4-200UG
Supplier Catalog Number:
LG5-H82E4-200ug
Alternative Catalog Number:
ABS-LG5-H82E4-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
LGR5 (also known as GPR49) is a seventransmembrane protein of the class A Rhodopsinlike family of GPCRs. LGR5 and LGR4 bind the Rspondins with high affinity and mediate the potentiation of Wnt/betacatenin signaling by enhancing Wntinduced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. - Proteine/Peptide
