Human LILRA6 / CD85b / ILT8 Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-LI6-H52H3-1MG
Supplier Catalog Number:
LI6-H52H3-1mg
Alternative Catalog Number:
ABS-LI6-H52H3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 (ILT5) and LILRA6 (ILT8) are highly polymorphic receptors with similar extracellular domains. LILRA6 can signal through association with an activating adaptor molecule, FcRgamma, which bears a cytoplasmic tail with an immunoreceptor tyrosinebased activation motif. Analysis of mRNA expression in the major fractions of PBMCs showed that LILRA6 is primarily expressed in monocytes, and its expression level correlates with copy number of the gene. - Proteine/Peptide
Human LILRA6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
* VAT and and shipping costs not included. Errors and price changes excepted