Human LIGHT / TNFSF14 Protein, His Tag, Ultra Low Endotoxin (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-LIT-H5243-1MG
Supplier Catalog Number:
LIT-H5243-1mg
Alternative Catalog Number:
ABS-LIT-H5243-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell costimulation signals effecting CTLmediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmunelike disease syndromes. - Proteine/Peptide