Human LRRC32 / GARP / Garpin Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human LRRC32 / GARP / Garpin Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-LR2-H5256-100UG
• Supplier Catalog Number: LR2-H5256-100ug
• Alternative Catalog Number: ABS-LR2-H5256-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Leucinerich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naive T cells. LRRC32 binds directly to the TGFbeta latency associated peptide (LAP) and tethers latent TGFbeta on the surface of activated Treg cells. The presentation of TGFbeta on Tregs contributes to their ability to suppress naive T cell proliferation. - Proteine/Peptide

Product Properties

• Molecular Weight: 92.4 kDa
• Tag: C-Fc
• NCBI: 14392
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: LRRC32

Images

LR2-H5256-100ug

Immobilized Human LRRC32, Fc Tag (Cat. No. LR2-H5256) at 2 µg/mL (100 µL/well) can bind Cynomolgus Latent TGF-Beta 1 (C33S), His Tag (Cat. No. TG1-C5243) with a linear range of 0.039-1.25 µg/mL (Routinely tested).

Human LRRC32, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.