Biotinylated Human LRP-6 (20-630) Protein, His,Avitag(TM)

Catalog Number: ABS-LR6-H82E7-25UG
Article Name: Biotinylated Human LRP-6 (20-630) Protein, His,Avitag(TM)
Biozol Catalog Number: ABS-LR6-H82E7-25UG
Supplier Catalog Number: LR6-H82E7-25ug
Alternative Catalog Number: ABS-LR6-H82E7-25UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
LRP6 is a transmembrane lowdensity lipoprotein receptor that shares a similar structure with LRP5. Lowdensity lipoprotein receptorrelated protein 6 is a key component of the LRP5/LRP6/Frizzled coreceptor group that is involved in canonical Wnt pathway. The Wntinduced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3Bcomplex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3mediated phosphorylation and destruction of betacatenin. - Proteine/Peptide
Molecular Weight: 72.5 kDa
Tag: C-10*His & C-Avi
NCBI: 75581
Buffer: PBS, pH7.4
Expression System: Ala 20 - Pro 630
Purity: 90%
Form: Powder
Target: LRP-6
LR6-H82E7-25ug