lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200MR6 and DEC205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical antitumor activity in lymphoma. After being verified as a single drug in vivo, the antibodydrug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anticd20 monoclonal antibody rituximab. - Proteine/Peptide
