Human Melanotransferrin / CD228 Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human Melanotransferrin / CD228 Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-MEN-H5223-1MG
• Supplier Catalog Number: MEN-H5223-1mg
• Alternative Catalog Number: ABS-MEN-H5223-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Melanotransferrin (MTF), also known as CD228, P97, MELTF and MFI2, is a cellsurface glycoprotein found on melanoma cells. The protein shares sequence similarity and ironbinding properties with members of the transferrin superfamily. Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. MTF expression is low in normal tissues but high in tumor and embryonic tissues. In melanoma MTF is associated with tumor metastasis and angiogenesis and upregulated in lung cancer tissue and cell lines. In the brain MTF is expressed in capillary endothelium but also in the reactive microglia associated with senile plaques in Alzheimers disease (AD). - Proteine/Peptide

Product Properties

• Molecular Weight: 39.3 kDa
• Tag: C-6*His
• NCBI: 08582
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Melanotransferrin

Images

Human Melanotransferrin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.