Biotinylated Human HGF R / c-MET Protein, His,Avitag(TM)
Biozol Catalog Number:
ABS-MET-H82E3-25UG
Supplier Catalog Number:
MET-H82E3-25ug
Alternative Catalog Number:
ABS-MET-H82E3-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the protooncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers - Proteine/Peptide
Immobilized Biotinylated Human HGF R Protein, His,Avitag (Cat. No. MET-H82E3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human HGF, Fc Tag (Cat. No. HGF-H5253) with a linear range of 0.2-2 ng/mL (QC tested).
Immobilized Human HGF, Fc Tag (Cat. No. HGF-H5253) at 2 µg/mL (100 µL/well) can bind Biotinylated Human HGF R Protein, His,Avitag (Cat. No. MET-H82E3) with a linear range of 1-31 ng/mL (Routinely tested).
Biotinylated Human HGF R Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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