MHC class I polypeptiderelated sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Iglike C1type (immunoglobulinlike) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta2microglobulin. MICA acts as a stressinduced selfantigen that is recognized by gamma delta Tcells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis. - Proteine/Peptide
Immobilized Human NKG2D, His Tag (Cat. No. NKD-H5245) at 2 µg/mL (100 µL/well) can bind Human MICA, Fc Tag (Cat. No. MIA-H5253) with a linear range of 0.4-2 ng/mL (QC tested).
Immobilized Human MICA, Fc Tag (Cat. No. MIA-H5253) at 1 µg/mL (100 µL/well) can bind Human NKG2D, Mouse IgG2a Fc Tag (Cat. No. NKD-H5259) with a linear range of 0.6-20 ng/mL (Routinely tested).
Human MICA, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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