Human MICA (24-309) Protein, Fc Tag (MALS verified), Unconjugated

Catalog Number: ABS-MIA-H5254-1MG
Article Name: Human MICA (24-309) Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-MIA-H5254-1MG
Supplier Catalog Number: MIA-H5254-1mg
Alternative Catalog Number: ABS-MIA-H5254-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
MHC class I polypeptiderelated sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Iglike C1type (immunoglobulinlike) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta2microglobulin. MICA acts as a stressinduced selfantigen that is recognized by gamma delta Tcells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis. - Proteine/Peptide
Molecular Weight: 59.4 kDa
Tag: C-Fc
NCBI: 29983
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity: 90%
Form: Powder
Target: MICA
Immobilized Human MICA (24-309) Protein, Fc Tag (Cat. No. MIA-H5254) at 1 µg/mL (100 µL/well) can bind Human NKG2D, Mouse IgG2a Fc Tag (Cat. No. NKD-H5259) with a linear range of 0.01-0.156 µg/mL (QC tested).
Immobilized Human NKG2D, His Tag (Cat. No. NKD-H5245) at 2 µg/mL (100 µL/well) can bind Human MICA (24-309) Protein, Fc Tag (Cat. No. MIA-H5254) with a linear range of 0.1-2 ng/mL (Routinely tested).
Human MICA (24-309) Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.