Human MMP-9 (107-707) (Q279R) Protein, His Tag (active enzyme), Unconjugated 1 mg

Product Overview

• Article Name: Human MMP-9 (107-707) (Q279R) Protein, His Tag (active enzyme), Unconjugated 1 mg
• Biozol Catalog Number: ABS-MM9-H52H8-1MG
• Supplier Catalog Number: MM9-H52H8-1mg
• Alternative Catalog Number: ABS-MM9-H52H8-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Matrix metallopeptidase 9 (MMP9) is also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), CLG4B, is secreted from neutrophils, macrophages, and a number of transformed cells, and is the most complex family member in terms of domain structure and regulation of its activity. . Structurally, MMP9 maybe be divided into five distinct domains: a prodomain which is cleaved upon activation, a gelatinbinding domain consisting of three contiguous fibronectin type II units, a catalytic domain containing the zinc binding site, a prolinerich linker region, and a carboxyl terminal hemopexinlike domain. This enzyme degrades various substrates including gelatin, collagen types IV and V, and elastin. MMP9 is involved in a variety of autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis, and be regarded as a potential therapeutic target. - Proteine/Peptide

Product Properties

• Molecular Weight: 68.5 kDa
• Tag: C-10*His
• NCBI: 14780
• Buffer: 25 mM Tris, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Liquid
• Target: MMP-9

Images

Human MMP-9 (107-707) (Q279R) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.