Human Neprilysin / MME / CD10 Protein, Tag Free (active enzyme), Unconjugated

Product Overview

• Article Name: Human Neprilysin / MME / CD10 Protein, Tag Free (active enzyme), Unconjugated
• Biozol Catalog Number: ABS-MME-H521B-1MG
• Supplier Catalog Number: MME-H521b-1mg
• Alternative Catalog Number: ABS-MME-H521B-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Cluster of differentiation 10 (CD10) is also known as membrane metalloendopeptidase, neutral endopeptidase (NEP), Neprilysin, and common acute lymphoblastic leukemia antigen (CALLA), is a 90110kDa type II transmembrane glycoprotein normally expressed by a variety of tissues, including epithelial cells of the prostate, kidney, intestine, endometrium, adrenal glands, and lung. This zincdependent metalloprotease enzyme cleaves peptide bonds on the amino side of hydrophobic residues and inactivates a variety of physiologically active secreted peptides. CD20 is thought to be the ratelimiting degrading enzyme of amyloid beta peptide (Abeta) whose abnormal misfolding and aggregation in neural tissue has been implicated in the development of Alzheimers disease (AD). CD10 is also identified as the common acute lymphoblastic leukemia antigen (CALLA) present on leukemic cells of preB phenotype, and thus serves as the most important biomarker in the diagnosis of human acute lymphocytic leukemia (ALL). - Proteine/Peptide

Product Properties

• Molecular Weight: 80.0 kDa
• Tag: Native
• NCBI: 000893
• Buffer: 20 mM Tris, 100 mM NaCl, pH8.0
• Purity: 95%
• Form: Powder
• Target: Neprilysin

Images

Human Neprilysin, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.