Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04), Unconjugated, Human

Catalog Number: ABS-MMF-MY2219-1MG
Article Name: Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04), Unconjugated, Human
Biozol Catalog Number: ABS-MMF-MY2219-1MG
Supplier Catalog Number: MMF-MY2219-1mg
Alternative Catalog Number: ABS-MMF-MY2219-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Antikörper
Species Reactivity: Rabbit
Conjugation: Unconjugated
Monomethyl auristatin F (MMAF) is a potent mitotic inhibitor that inhibits tubulin polymerization. MMAF is widely used as a cytotoxic component of antibodydrug conjugates (ADCs) to treat several cancer types. AntiMMAF antibody is a rabbit monoclonal antibody specifically reacts with MMAF without MMAE, which is more sensitive than mouse antibody. The antiMMAF antibody is a useful reagent in PK assay to determine conjugated antibodies. - Antikörper
Tag: Rabbit IgG | Rabbit Kappa
Buffer: PBS, pH7.4
Form: Powder
Target: MMAF
Immobilized Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) (Cat. No. MMF-MY2219) at 1 µg/mL (100 µL/well) can bind IgG1-MMAF with a linear range of 0.1-4 ng/mL (QC tested).
Serial dilutions of MMAF were added into Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) (Cat. No. MMF-MY2219): IgG1-MMAF binding reactions. The half maximal inhibitory concentration (IC50) is 0.09234 µg/mL (Routinely tested).
Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.