Human NK2R Full Length Protein (VLP), Unconjugated
Biozol Catalog Number:
ABS-NKR-H52P3-100UG
Supplier Catalog Number:
NKR-H52P3-100ug
Alternative Catalog Number:
ABS-NKR-H52P3-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
NK2R is a G proteincoupled receptor with high affinity for the tachykinin Substance K (Neurokinin A). Upon activation, it triggers a phosphatidylinositolcalcium signaling pathway, leading to intracellular calcium release. The receptors binding affinity follows the order: Substance K > Neuromedin K > Substance P. NK2R also regulates energy metabolism and has shown significant potential in appetite control. Due to its diverse functions, it is considered a promising therapeutic target for conditions such as asthma, irritable bowel syndrome, obesity, and type 2 diabetes. - Proteine/Peptide