Human NME1 / NDKA / NM23-H1 Protein, His Tag, Unconjugated, E. coli

Product Overview

• Article Name: Human NME1 / NDKA / NM23-H1 Protein, His Tag, Unconjugated, E. coli
• Biozol Catalog Number: ABS-NM1-H5147-1MG
• Supplier Catalog Number: NM1-H5147-1mg
• Alternative Catalog Number: ABS-NM1-H5147-1MG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Nucleoside diphosphate kinase A, a member of the NDK family, is also known as NME1, NDP kinase A (NDPA), granzyme Aactivated DNase (GAAD), metastasis inhibition factor nm23 (NM23H1) and tumor metastatic processassociated protein. NME1 plays a major role in the synthesis of nucleoside triphosphates other than ATP. NME1 is also involved in cell proliferation, differentiation and development, signal transduction, G proteincoupled receptor endocytosis, and gene expression. Furthermore, NME1 is required for neural development including neural patterning and cell fate determination. During GZMAmediated cell death, NME1 works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3 end to enhance DNA damage and prevent DNA end reannealing and rapid repair. - Proteine/Peptide

Product Properties

• Molecular Weight: 18.0 kDa
• Tag: N-6*His
• NCBI: 00293
• Buffer: PBS, pH7.4
• Purity: 98%
• Form: Powder
• Target: NME1

Images

Human NME1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.