Human NPTX2 Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-NP2-H52H6-100UG
Supplier Catalog Number:
NP2-H52H6-100ug
Alternative Catalog Number:
ABS-NP2-H52H6-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Neuronal Pentraxin 2 (NPTX2), also named neuronal activityreg ulated pentraxin, is a secreted glycoprotein characterized by a cyclic multimeric structure. In vivo, NTPX2 exerts various neurological effects by combining with the transmembrane protein neuronal pen traxin receptor (NPTXR). NPTX2 was thought to play a vital role in transmitting neurotrans mitters and maintaining synaptic plasticity. It also plays a role in clustering of alphaamino3hydroxy5methyl4isoxazolepropionic acid (AMPA)type glutamate receptors at established synapses, resulting in nonapoptotic cell death of dopaminergic nerve cells. Upregulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. - Proteine/Peptide
Human NPTX2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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