Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-NR1-H5252-1MG
• Supplier Catalog Number: NR1-H5252-1mg
• Alternative Catalog Number: ABS-NR1-H5252-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Neuropilin1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membranebound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF2 isoform of PGF, The VEGF165 isoform of VEGF and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. It may regulate VEGFinduced angiogenesis. The soluble isoform 2 binds VEGF165 and appears to inhibit its binding to cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 96.5 kDa
• Tag: C-Fc
• NCBI: 07533
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Neuropilin-1

Images

Immobilized Human VEGF165, premium grade (Cat. No. VE5-H4210) at 2 µg/mL (100 µL/well) can bind Human NRP1, Fc Tag (Cat. No. NR1-H5252) with a linear range of 0.2-3 ng/mL (QC tested).

Immobilized Human NRP1, Fc Tag (Cat. No. NR1-H5252) at 2 µg/mL (100 µL/well) can bind Biotinylated Human VEGF165, His,Avitag (Cat. No. VE5-H82Q0) with a linear range of 0.008-0.25 µg/mL (Routinely tested).

Human NRP1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

NR1-H5252-1mg