Human NY-ESO-1 TCR Protein, Fc Tag (MALS & SPR verified), Unconjugated
Biozol Catalog Number:
ABS-NYR-H5258-25UG
Supplier Catalog Number:
NYR-H5258-25ug
Alternative Catalog Number:
ABS-NYR-H5258-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
NYESO1 is one of the most recognized tumor antigens in immunotherapy. Its expression is strictly limited to male germ cells and multiple malignant tumor cells, with virtually no presence in normal somatic cells. This unique expression profile makes it an ideal target for Tcell receptor (TCR) therapy. NYESO1 specific TCR can bind to NYESO1 peptides presented by MHC molecules, and clinical trials have demonstrated significant efficacy of NYESO1 targeted TCRT therapy in advanced sarcomas and other malignancies. - Proteine/Peptide
Molecular Weight:
49.3 kDa & 53.2 kDa
Tag:
C-Fc
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity:
90%
Form:
Powder
Target:
NY-ESO-1 TCR
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