Human Osteopontin (OPN) Protein, His Tag, premium grade, Unconjugated

Product Overview

• Article Name: Human Osteopontin (OPN) Protein, His Tag, premium grade, Unconjugated
• Biozol Catalog Number: ABS-OPN-H5227-100UG
• Supplier Catalog Number: OPN-H5227-100ug
• Alternative Catalog Number: ABS-OPN-H5227-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Osteopontin (OPN) is also known as Secreted phosphoprotein 1 (SPP1), Bone sialoprotein 1, Nephropontin, Urinary stone protein, Uropontin, BNSP, which belongs to the osteopontin family. OPN / SPP1 is a highly negatively charged, extracellular matrix protein that lacks an extensive secondary structure. Full length OPN (OPNFL) can be modified by thrombin cleavage, which exposes a cryptic sequence, SVVYGLR on the cleaved form of the protein known as OPNR. Osteopontin / SPP1 is biosynthesized by a variety of tissue types. OPN is the ligand for integrin alphaV/beta3. OPN / SPP1 binds tightly to hydroxyapatite and appears to form an integral part of the mineralized matrix. OPN / SPP1 probably important to cellmatrix interaction. OPN / SPP1 acts as a cytokine involved in enhancing production of interferongamma and interleukin12 and reducing production of interleukin10 and is essential in the pathway that leads to type I immunity. - Proteine/Peptide

Product Properties

• Molecular Weight: 33.0 kDa
• Tag: C-6*His
• NCBI: 07016
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Osteopontin

Images

Human Osteopontin, His Tag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.