SARS-CoV-2 ORF8 Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-OR8-C52H1-1MG
Supplier Catalog Number:
OR8-C52H1-1mg
Alternative Catalog Number:
ABS-OR8-C52H1-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Virus
Conjugation:
Unconjugated
Alternative Names:
sars-cov-2
The viral protein encoded by open reading frame 8 (ORF8) of SARSCoV2, which shares the least homology with SARSCoV among all viral proteins, directly interacts with MHC molecules and mediates their downregulation. In ORF8expressing cells, MHC molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARSCoV2-infected cells are much less sensitive to lysis by cytotoxic T lymphocytes. - Proteine/Peptide
SARS-CoV-2 ORF8 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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