Human OX40 Ligand / TNFSF4 Protein, His Tag, active trimer (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-OXL-H52Q8-1MG
Supplier Catalog Number:
OXL-H52Q8-1mg
Alternative Catalog Number:
ABS-OXL-H52Q8-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionallyactivated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membranebound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart. - Proteine/Peptide
Immobilized Human OX40 Ligand Protein, His Tag (Cat. No. OXL-H52Q8) at 2 µg/mL (100 µL/well) can bind Human OX40, Fc Tag (Cat. No. OX0-H5255) with a linear range of 1-8 ng/mL (QC tested).
Immobilized Human OX40 Ligand Protein, His Tag (Cat. No. OXL-H52Q8) at 2 µg/mL (100 µL/well) can bind Biotinylated Human OX40, Fc,Avitag (Cat. No. OX0-H82F7) with a linear range of 10-78 ng/mL (Routinely tested).
Human OX40 Ligand Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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