Programmed cell death 1 ligand 1 (PDL1) is also known as B7H, B7H1, MGC142294, MGC142296, PDL1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Iglike domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing Tcell responses by inducing apoptosis and arresting cellcycle progression. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Purity:
90%
Form:
Powder
Target:
PD-L1
Immobilized Anti-PD-L1 Antibody, Human IgG1 at 5 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus / Rhesus macaque PD-L1 Protein, Fc,Avitag (Cat. No. PD1-C82F3) with a linear range of 0.1-4 ng/mL (QC tested).
Immobilized Biotinylated Cynomolgus / Rhesus macaque PD-L1 Protein, Fc,Avitag (Cat. No. PD1-C82F3) at 5 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Cynomolgus PD-1, His Tag (Cat. No. PD1-C52H5) with a linear range of 0.02-0.63 µg/mL (Routinely tested).
Biotinylated Cynomolgus / Rhesus macaque PD-L1 Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
PD1-C82F3-200ug
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