Human PD-L1 / B7-H1 Protein, Mouse IgG1 Fc Tag, low endotoxin (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-PD1-H52A3-100UG
Supplier Catalog Number:
PD1-H52A3-100ug
Alternative Catalog Number:
ABS-PD1-H52A3-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Programmed cell death 1 ligand 1 (PDL1) is also known as B7H, B7H1, MGC142294, MGC142296, PDL1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Iglike domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing Tcell responses by inducing apoptosis and arresting cellcycle progression. - Proteine/Peptide
Immobilized Human PD-1 Protein, Fc Tag (Cat. No. PD1-H5257) at 1 µg/mL (100 µL/well) can bind Human PD-L1 Protein, Mouse IgG1 Fc Tag (Cat. No. PD1-H52A3) with a linear range of 0.008-0.25 µg/mL (QC tested).
Serial dilutions of Nivolumab were added into Human PD-L1 Protein, Mouse IgG1 Fc Tag (Cat. No. PD1-H52A3): Biotinylated Human PD-1, Fc,Avitag,His Tag (Cat. No. PD1-H82F2) binding reactions. The half maximal inhibitory concentration (IC50) is 0.38426 µg/mL (QC tested).
PD1-H52A3-100ug
Human PD-L1 Protein, Mouse IgG1 Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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