Human PD-L2 / B7-DC Protein, Fc Tag (MALS verified), Unconjugated

Catalog Number: ABS-PD2-H5251-100UG
Article Name: Human PD-L2 / B7-DC Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-PD2-H5251-100UG
Supplier Catalog Number: PD2-H5251-100ug
Alternative Catalog Number: ABS-PD2-H5251-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Programmed cell death 1 ligand 2 (PDL2 or PDCD1 ligand 2) is also known as Butyrophilin B7DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PDL2 is upregulated by IFNG/IFNgamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. PDL2 Involved in the costimulatory signal, essential for Tcell proliferation and IFNG production in a PDCD1independent manner. PDL2 interaction with PDCD1 inhibits Tcell proliferation by blocking cell cycle progression and cytokine production. - Proteine/Peptide
Molecular Weight: 49.2 kDa
Tag: C-Fc
NCBI: 13679
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: PD-L2
PD2-H5251-100ug
Human PD-L2 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.