Biotinylated Human PD-L2 / B7-DC Protein, Avitag(TM),His Tag (recommended for biopanning)

Product Overview

• Article Name: Biotinylated Human PD-L2 / B7-DC Protein, Avitag(TM),His Tag (recommended for biopanning)
• Biozol Catalog Number: ABS-PD2-H82E8-25UG
• Supplier Catalog Number: PD2-H82E8-25ug
• Alternative Catalog Number: ABS-PD2-H82E8-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Programmed cell death 1 ligand 2 (PDL2 or PDCD1 ligand 2) is also known as Butyrophilin B7DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PDL2 is upregulated by IFNG/IFNgamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. PDL2 Involved in the costimulatory signal, essential for Tcell proliferation and IFNG production in a PDCD1independent manner. PDL2 interaction with PDCD1 inhibits Tcell proliferation by blocking cell cycle progression and cytokine production. - Proteine/Peptide

Product Properties

• Molecular Weight: 25.2 kDa
• Tag: C-Avi & C-6*His
• NCBI: 13679
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: PD-L2

Application Notes

• Application Notes: PD2-H82E8 works best for experiments that test the binding between PD-L2 and candidate antibodies, such as biopanning and other relevant assays. This product is NOT suitable for testing PD1-PDL2 binding. For this type of application, we strongly recommend you to choose PD2-H82F6 as an alternative.

Images

Immobilized Anti-PD-L2 MAb (human IgG1) at 2 µg/mL (100 µL/well) can bind Biotinylated Human PD-L2, Avitag,His Tag (Cat. No. PD2-H82E8) with a linear range of 2-50 ng/mL (QC tested).

Biotinylated Human PD-L2, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.