Mouse PD-L2 / B7-DC Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-PD2-M52E3-1MG
Supplier Catalog Number:
PD2-M52E3-1mg
Alternative Catalog Number:
ABS-PD2-M52E3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Unconjugated
Programmed cell death 1 ligand 2 (PDL2 or PDCD1 ligand 2) is also known as Butyrophilin B7DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PDL2 is upregulated by IFNG/IFNgamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. PDL2 Involved in the costimulatory signal, essential for Tcell proliferation and IFNG production in a PDCD1independent manner. PDL2 interaction with PDCD1 inhibits Tcell proliferation by blocking cell cycle progression and cytokine production. - Proteine/Peptide
Immobilized Biotinylated Human PD-1, Fc Tag (Cat. No. PD1-H82F1) at 1 µg/mL (100 µL/well) on streptavidin precoated (0.2 µg/well) plate, can bind Mouse PD-L2, His Tag (Cat. No. PD2-M52E3) with a linear range of 20-156 ng/mL (QC tested).
Immobilized Mouse PD-L2, His Tag (Cat. No. PD2-M52E3) at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse PD-1, Fc,Avitag (Cat. No. PD1-M82F4) with a linear range of 0.156-2.5 µg/mL (Routinely tested).
Mouse PD-L2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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