Human PDE4A Protein, His Tag (MALS verified), Unconjugated, Insect 50 ug

Product Overview

• Article Name: Human PDE4A Protein, His Tag (MALS verified), Unconjugated, Insect 50 ug
• Biozol Catalog Number: ABS-PDA-H55H3-50UG
• Supplier Catalog Number: PDA-H55H3-50ug
• Alternative Catalog Number: ABS-PDA-H55H3-50UG
• Manufacturer: AcroBiosystems
• Host: Insect
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

cAMPspecific 3,5cyclic phosphodiesterase 4A (PDE4A) is an enzyme that in humans is encoded by the PDE4A gene. It belongs to the PDE family who hydrolyze 3'5'cyclic adenosine monophosphate (cyclic AMP) to 5'adenosine monophosphate (AMP). PDE enzyme family plays a pivotal role in regulating levels of the second messenger cAMP. Consequently, PDE4 inhibitors have been investigated as a therapeutic strategy to enhance cAMP signaling in a broad range of diseases, including several types of cancers, as well as in various neurologic, dermatological, and inflammatory diseases. - Proteine/Peptide

Product Properties

• Molecular Weight: 47.1 kDa
• Tag: C-10*His
• NCBI: 27815
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Liquid
• Target: PDE4A

Images

Human PDE4A Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.