Human Perlecan Protein, His Tag, low endotoxin, Unconjugated

Product Overview

• Article Name: Human Perlecan Protein, His Tag, low endotoxin, Unconjugated
• Biozol Catalog Number: ABS-PEN-H5245-1MG
• Supplier Catalog Number: PEN-H5245-1mg
• Alternative Catalog Number: ABS-PEN-H5245-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Siglec15 is a transmembrane glycoprotein belonging to the Siglec family, recognized for its sialic acidbinding properties and role in immune regulation. Structurally, its extracellular domain contains two Iglike domains, and it functionally associates with the signaling adaptors DAP12 and DAP10. Siglec15 is expressed on immune cells, including osteoclasts, macrophages, and dendritic cells. It exerts its function by binding to its ligand, the sialylTn antigen. This interaction is critical for inducing TGFbeta production by tumorassociated macrophages and plays an essential role in osteoclast formation and TRANCE/RANK Ligand signaling. - Proteine/Peptide

Product Properties

• Molecular Weight: 12.2 kDa
• Tag: N-10*His
• NCBI: 98160
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Perlecan

Images

Human Perlecan Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.