Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-PGN-H52H3-100UG
• Supplier Catalog Number: PGN-H52H3-100ug
• Alternative Catalog Number: ABS-PGN-H52H3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene. Progranulin consists of seven and a half, tandemly repeated, nonidentical copies of the 12 cysteine granulin motif. Many cellular processes and diseases are associated with this unique pleiotropic factor that include, but are not limited to, embryogenesis, tumorigenesis, inflammation, wound repair, neurodegeneration and lysosome function. Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia. - Proteine/Peptide

Product Properties

• Molecular Weight: 63.7 kDa
• Tag: C-10*His
• NCBI: 28799
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Progranulin

Images

Human Progranulin Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

PGN-H52H3-100ug