Human Hyaluronidase PH-20 / SPAM1 Protein, Tag Free (active enzyme, MALS verified), Unconjugated

Product Overview

• Article Name: Human Hyaluronidase PH-20 / SPAM1 Protein, Tag Free (active enzyme, MALS verified), Unconjugated
• Biozol Catalog Number: ABS-PH0-H5219-1MG
• Supplier Catalog Number: PH0-H5219-1mg
• Alternative Catalog Number: ABS-PH0-H5219-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Hyaluronidase PH20 is also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH20 is expressed in testis. SPAM1 / PH20 random hydrolysis of (1>4)linkages between N - acetyl - beta - D - glucosamine and Dglucuronate residues in hyaluronate. SPAM1 / PH20 involved in spermegg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. - Proteine/Peptide

Product Properties

• Molecular Weight: 52.6 kDa
• Tag: Native
• NCBI: 38567
• Buffer: 50 mM Tris, 100 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Hyaluronidase PH-20

Images

Human Hyaluronidase PH-20 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.