Human PLAU / uPA Protein, His Tag (activated by trypsin) (active enzyme), Unconjugated

Product Overview

• Article Name: Human PLAU / uPA Protein, His Tag (activated by trypsin) (active enzyme), Unconjugated
• Biozol Catalog Number: ABS-PLU-H5228-1MG
• Supplier Catalog Number: PLU-H5228-1mg
• Alternative Catalog Number: ABS-PLU-H5228-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Urokinase type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys - Pro - Gly Arg560 Val561 - Val - Gly - Gly - Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). - Proteine/Peptide

Product Properties

• Molecular Weight: 15.3 kDa, 17.8 kDa and 29.2 kDa
• Tag: C-6*His
• NCBI: 00749
• Buffer: 25 mM HEPES, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: PLAU

Images

Human PLAU, His Tag (activated by trypsin) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.