Human Prolactin / PRL Protein, Mouse IgG2a Fc Tag, low endotoxin, Unconjugated

Product Overview

• Article Name: Human Prolactin / PRL Protein, Mouse IgG2a Fc Tag, low endotoxin, Unconjugated
• Biozol Catalog Number: ABS-PRN-H5257-100UG
• Supplier Catalog Number: PRN-H5257-100ug
• Alternative Catalog Number: ABS-PRN-H5257-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds. Excessive secretion of prolactin hyperprolactinemia is a relative common disorder in humans. This condition has numerous causes, including prolactinsecreting tumors and therapy with certain drugs. The prolactin receptor (gene name PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Expression of the prolactin receptor is widespread. Each prolactin molecule is thought to bind two receptor molecules - Proteine/Peptide

Product Properties

• Molecular Weight: 49.8 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 5
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Prolactin

Images

Immobilized Human Prolactin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PRN-H5257) at 1 µg/mL (100 µL/well) can bind Human Prolactin R Protein, Fc Tag (Cat. No. PRP-H5251) with a linear range of 2-78 ng/mL (QC tested).

Human Prolactin Protein, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.