Human Prolactin R / PRLR Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human Prolactin R / PRLR Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-PRP-H5251-1MG
• Supplier Catalog Number: PRP-H5251-1mg
• Alternative Catalog Number: ABS-PRP-H5251-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

As a transmembrane receptor, the prolactin receptor (PRLR) interacts with prolactin. In addition, the PRLR also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures. - Proteine/Peptide

Product Properties

• Molecular Weight: 51.0 kDa
• Tag: C-Fc
• NCBI: 16471
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Prolactin R

Images

Immobilized Human Prolactin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. PRN-H5257) at 1 µg/mL (100 µL/well) can bind Human Prolactin R Protein, Fc Tag (Cat. No. PRP-H5251) with a linear range of 2-78 ng/mL (QC tested).

Immobilized Human GH, Tag Free at 2 µg/mL (100 µL/well) can bind Human Prolactin R, Fc Tag (Cat. No. PRP-H5251) with a linear range of 0.4-6 ng/mL (Routinely tested).

Human Prolactin R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.