Human PSME3 / PA28g Protein, His Tag, Unconjugated, E. coli

Product Overview

• Article Name: Human PSME3 / PA28g Protein, His Tag, Unconjugated, E. coli
• Biozol Catalog Number: ABS-PS3-H5142-100UG
• Supplier Catalog Number: PS3-H5142-100ug
• Alternative Catalog Number: ABS-PS3-H5142-100UG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REGgamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsinlike catalytic subunit of the proteasome but inhibits the chymotrypsinlike and postglutamylpreferring (PGPH) subunits. PSME3 can also facilitate the MDM2p53/TP53 interaction which promotes ubiquitination and MDM2dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation. - Proteine/Peptide

Product Properties

• Molecular Weight: 30.3 kDa
• Tag: N-6*His
• NCBI: 61289
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: PSME3

Images

Human PSME3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.