Mouse PSMA / FOLH1 Protein, Fc Tag (MALS verified), Unconjugated, Human

Product Overview

• Article Name: Mouse PSMA / FOLH1 Protein, Fc Tag (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-PSA-M5266-1MG
• Supplier Catalog Number: PSA-M5266-1mg
• Alternative Catalog Number: ABS-PSA-M5266-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

Prostatespecific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), Nacetylatedalphalinked acidic dipeptidase I (ALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP2 is homodimer and binds 2 zinc ions per subunit, and required for ALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, Cterminal glutamyl residue, typically from AcAspGlu or folylpoly - gamma glutamates. FOLH1 / GCP2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked acidic dipeptidase (ALADase) activity and has a preference for trialphaglutamate peptides. GCP2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidylpeptidase IV type activity. In vitro, cleaves GlyProAMC. - Proteine/Peptide

Product Properties

• Molecular Weight: 106.0 kDa
• Tag: N-Fc
• NCBI: 35409
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: PSMA

Images

Mouse PSMA Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.