Human PVRIG (poliovirus receptor related immunoglobulin domaincontaining protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptorlike protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses Tcell receptormediated signals. - Proteine/Peptide
Immobilized Biotinylated Human PVRIG, His,Avitag (Cat. No. PVG-H82E3) at 1 µg/mL (100 µL/well) on Streptavidin precoated (0.5 µg/well) plate, can bind Human Nectin-2, Fc Tag (Cat. No. PV2-H5253) with a linear range of 0.1-5 ng/mL (QC tested).
Biotinylated Human PVRIG, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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