Anti-Rituximab Antibody (AY37) (recommended for PK/PD), Unconjugated, Multiple

Catalog Number: ABS-RIB-Y37-100UG
Article Name: Anti-Rituximab Antibody (AY37) (recommended for PK/PD), Unconjugated, Multiple
Biozol Catalog Number: ABS-RIB-Y37-100UG
Supplier Catalog Number: RIB-Y37-100ug
Alternative Catalog Number: ABS-RIB-Y37-100UG
Manufacturer: AcroBiosystems
Host: Multiple
Category: Antikörper
Species Reactivity: Mouse
Conjugation: Unconjugated
Rituxan is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavychain variable region sequences and human constant region sequences. Rituximab is composed of two heavy chains of 451 amino acids and two light chains of 213 amino acids - Antikörper
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 0.95
Form: Powder
Target: Rituximab
Detection of rituximab by bridging ELISA in serum. Immobilized Anti-Rituximab Antibody (AY37) (Cat. No. RIB-Y37) at 2 µg/mL, add increasing concentrations of rituximab (10% human serum) and then add Biotinylated Anti-Rituximab Antibody (Cat. No. RIB-BY35) at 1 µg/mL. Detection was performed using HRP-conjugated streptavidin with a sensitivity of 1 ng/mL (QC tested).
Demonstration of the specificity of Anti-Rituximab Antibody (AY37) (Cat. No. RIB-Y37) to the rituximab.
Anti-Rituximab Antibody (AY37) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.