Human RNF43 Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human RNF43 Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-RN3-H5256-100UG
• Supplier Catalog Number: RN3-H5256-100ug
• Alternative Catalog Number: ABS-RN3-H5256-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

E3 ubiquitinprotein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and noncanonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity) - Proteine/Peptide

Product Properties

• Molecular Weight: 43.5 kDa
• Tag: C-Fc
• NCBI: 68
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: RNF43

Images

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Human RNF43, Fc Tag (Cat. No. RN3-H5256) with a linear range of 2-20 ng/mL (QC tested).

Immobilized Human R-Spondin 3 (22-146), His Tag (Cat. No. RS6-H5222) at 5 µg/mL (100 µL/well) can bind Human RNF43, Fc Tag (Cat. No. RN3-H5256) with a linear range of 0.3-5 ng/mL (Routinely tested).

Human RNF43, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.