The two major glycoproteins on the surface of the RSV virion, the attachment glycoprotein (G) and the fusion (F) glycoprotein, control the initial phases of infection. The central region of the G protein contains a 13amino acid highly conserved domain, partially overlapping the cysteine noose domain with 4 cysteines linked 1-4 and 2-3, followed by a highly basic heparinbinding domain (HBD). The HBD is the likely attachment site for heparan sulfate (HS) found on the surface of most cells. A peptide from the G protein HBD (amino acids 184-198) binds efficiently to HEp2 cells and inhibits RSV infection. - Antikörper
Tag:
Human IgG1 | Human Kappa
Buffer:
PBS, pH7.4
Purity:
0.95
Form:
Powder
Target:
HRSV Glycoprotein (RSV-G)
Immobilized HRSV (A) Glycoprotein G Protein, His Tag (Cat. No. RSG-V5221) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) (Cat. No. RSV-MY2231) with a linear range of 0.06-2 ng/mL (QC tested).
Monoclonal Anti-HRSV Glycoprotein (RSV-G) Antibody, Human IgG1 (8E6) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
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