AntiSARSCoV2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARSCoV2 Spike S1 protein. As verified in competitive ELISAbased and pseudovirusbased neutralization assay, this chimeric monoclonal can potently neutralize all SARSCoV2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529). - Antikörper
Tag:
Human IgG1 | Human Kappa
Buffer:
PBS, pH7.4
Purity:
0.95
Form:
Powder
Target:
Spike RBD
Immobilized SARS-CoV-2 S1 protein, His Tag (Cat. No. S1N-C52H2) at 2 µg/mL (100 µL/well) can bind Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Cat. No. S1N-M122) with a linear range of 0.2-3 ng/mL (QC tested).
Detection of SARS-CoV-2 S protein RBD by Sandwich ELISA Assay.Immobilized Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Cat. No. S1N-M122) at 2 µg/mL (100 µL/well) can bind Spike RBD (Cat. No. SPD-C52H1). And then add Biotinylated Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) (Cat. No.S1N-M13L3) at 0.2 µg/mL. Detection was performed using HRP-conjugated streptavidin with sensitivity of 0.05 ng/mL (Routinely tested).
Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
S1N-M122-100ug
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