Human Serpin F1 / PEDF Protein, His Tag, Unconjugated
Biozol Catalog Number:
ABS-SE1-H5221-100UG
Supplier Catalog Number:
SE1-H5221-100ug
Alternative Catalog Number:
ABS-SE1-H5221-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
erpin F1 (SERPINF1) is also known as Pigment epitheliumderived factor (PEDF), Cell proliferationinducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions. - Proteine/Peptide
