Human Siglec-15 / CD33L3 Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human Siglec-15 / CD33L3 Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-SG5-H52H3-100UG
• Supplier Catalog Number: SG5-H52H3-100ug
• Alternative Catalog Number: ABS-SG5-H52H3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Siglec15 is a DAP12associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Iglike lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the Itype lectins. Siglec15 consisting of immunoglobulin (Ig)like domains, transmembrane domain and a short cytoplasmic tail. Siglec15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. - Proteine/Peptide

Product Properties

• Molecular Weight: 28.4 kDa
• Tag: C-10*His
• NCBI: 6
• Buffer: 25 mM MES, 150 mM NaCl, pH5.5
• Purity: 90%
• Form: Powder
• Target: Siglec-15

Images

Immobilized Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 1 µg/mL (100 µL/well) can bind Mouse Human chimeric mAb (5G12, Human IgG1) with a linear range of 0.2-2 ng/mL (QC tested).

Immobilized Human Siglec-15, His Tag (Cat. No. SG5-H52H3) at 10 µg/mL (100 µL/well) can bind Neu5Ac(a2-6)GalNAc-PAA-biotin with a linear range of 0.078-0.313 µg/mL (Routinely tested).

Human Siglec-15, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.