Human Siglec-10 Protein, Mouse IgG2a Fc Tag, low endotoxin, Unconjugated

Catalog Number: ABS-SI0-H525B-100UG
Article Name: Human Siglec-10 Protein, Mouse IgG2a Fc Tag, low endotoxin, Unconjugated
Biozol Catalog Number: ABS-SI0-H525B-100UG
Supplier Catalog Number: SI0-H525b-100ug
Alternative Catalog Number: ABS-SI0-H525B-100UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
The siglecs (sialic acidbinding Iglike lectins) are a distinct subset of the Ig superfamily with adhesionmoleculelike structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Iglike domains, a transmembrane domain, and a cytoplasmic tail containing two ITIMsignaling motifs. Siglec10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec10VAP1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products. - Proteine/Peptide
Molecular Weight: 85.6 kDa
Tag: C-mFc(mIgG2a)
NCBI: 96
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 95%
Form: Powder
Target: Siglec-10
Immobilized Human Siglec-10 Protein, Mouse IgG2a Fc Tag (Cat. No. SI0-H525b) at 5 µg/mL (100 µL/well) can bind Anti-Human Siglec-10 MAb, human IgG with a linear range of 0.6-20 ng/mL (QC tested).
Human Siglec-10 Protein, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.