Human Siglec-2 / CD22 (176-687) Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-SI2-H52H8-100UG
Supplier Catalog Number:
SI2-H52H8-100ug
Alternative Catalog Number:
ABS-SI2-H52H8-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Bcell receptor CD22 is also known as Sialic acidbinding Iglike lectin 2 (Siglec2), Blymphocyte cell adhesion molecule (BLCAM), Tcell surface antigen Leu14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Iglike lectin) family. CD22 mediates Bcell Bcell interactions, and may be involved in the localization of Bcells in lymphoid tissues. Siglec2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. - Proteine/Peptide
