Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag, low Endotoxin (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-SI7-H5257-500UG
Supplier Catalog Number:
SI7-H5257-500ug
Alternative Catalog Number:
ABS-SI7-H5257-500UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Siglec7 is a member of the human CD33-related Siglec receptor. The extracellular region of Siglec-7 is characterized by an N-terminal V-set Ig domain that can bind sialic acid and two C2-set Ig domains. The cytoplasmic tail of Siglec-7 has one immune-receptor tyrosine-based inhibitory motif (ITIM) and one ITIM-like motif. Siglec7 is considered as a sialic aciddependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells. - Proteine/Peptide