Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag, low Endotoxin (MALS verified), Unconjugated

Product Overview

• Article Name: Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag, low Endotoxin (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-SI7-H5258-500UG
• Supplier Catalog Number: SI7-H5258-500ug
• Alternative Catalog Number: ABS-SI7-H5258-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Siglec7 is a member of the human CD33-related Siglec receptor. The extracellular region of Siglec-7 is characterized by an N-terminal V-set Ig domain that can bind sialic acid and two C2-set Ig domains. The cytoplasmic tail of Siglec-7 has one immune-receptor tyrosine-based inhibitory motif (ITIM) and one ITIM-like motif. Siglec7 is considered as a sialic aciddependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 63.3 kDa
• Tag: C-Fc(A2)
• NCBI: 9
• Buffer: 25 mM MES, 150 mM NaCl, pH5.5
• Purity: 95%
• Form: Powder
• Target: Siglec-7

Images

Immobilized Human Siglec-7, Fc (L117A, L118A) Tag (Cat. No. SI7-H5258) at 5 µg/mL (100 µL/well) can bind Neu5Aca2-6GalNAca-PAA-biotin with a linear range of 0.01-0.625 µg/mL (QC tested).

Human Siglec-7, Fc (L117A, L118A) Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.