Human SIGIRR Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-SIR-H5255-1MG
Supplier Catalog Number:
SIR-H5255-1mg
Alternative Catalog Number:
ABS-SIR-H5255-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Single immunoglobulin IL1related receptor (SIGIRR), which is also known as Toll/interleukin1 receptor 8, is a member of the interleukin1 receptor (IL1R) family. SIGIRR acts as a negative regulator of the Tolllike and IL1R receptor signaling pathways. Attenuates the recruitment of receptorproximal signaling components to the TLR4 receptor, probably through an TIRTIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. - Proteine/Peptide
