Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Detergent), Unconjugated 500 ug

Product Overview

• Article Name: Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Detergent), Unconjugated 500 ug
• Biozol Catalog Number: ABS-SLS-H52D3-500UG
• Supplier Catalog Number: SLS-H52D3-500ug
• Alternative Catalog Number: ABS-SLS-H52D3-500UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised dipeptide cystine, requiring specialised transport systems for its import into the cell. System xc is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc is frequently upregulated, making it an attractive target for anticancer therapies. - Proteine/Peptide

Product Properties

• Molecular Weight: 59.4 kDa & 69.9 kDa
• Tag: N-Flag & C-10*His & N-10*His
• NCBI: 9
• Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Form: Liquid
• Target: SLC7A11 & SLC3A2

Images

Immobilized Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Cat. No. SLS-H52D3) at 5 µg/mL (100 µL/well) can bind Anti-SLC7A11Antibody with a linear range of 2-63 ng/mL (QC tested).

SLS-H52D3-500ug