Human SMN1 Protein, His Tag, Unconjugated, E. coli
Biozol Catalog Number:
ABS-SM1-H5145-100UG
Supplier Catalog Number:
SM1-H5145-100ug
Alternative Catalog Number:
ABS-SM1-H5145-100UG
Manufacturer:
AcroBiosystems
Host:
E. coli
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
SMN1 is produced chiefly by the SMN1 gene, located on the telomeric portion of chromosome 5q. SMN1 protein is one of a group of proteins called the SMN complex, which is important for the maintenance of specialized nerve cells called motor neurons. In cells, the SMN complex plays an important role in processing mRNA. The SMN complex helps to assemble the cellular machinery needed to process premRNA. The SMN complex is also important for the development of specialized outgrowths from nerve cells called dendrites and axons. Deletion or mutation of the SMN1 gene results in a reduced level of fulllength SMN protein and manifests as a range of neuromuscular phenotypes in humans as the disease spinal muscular atrophy (SMA). - Proteine/Peptide
Immobilized Human SMN1, His Tag (Cat. No. SM1-H5145) at 1 µg/mL (100 µL/well) can bind Anti-SMN1 antibody with a linear range of 0.2-8 ng/mL (QC tested).
Human SMN1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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